Using Photodynamic Therapy (PDT) to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

Chair of Thoracic Surgery at Roswell Park, Dr. Sai Yendamuri, shares insights into an exciting phase I trial evaluating the side effects of intraoperative photodynamic therapy (PDT) with porfimer sodium in enhancing the response to immunotherapy with an immune checkpoint inhibitor drug in patients with non-small cell lung cancer with pleural disease. Developed at Roswell Park, PDT is a technique that works by combining a photosensitizing agent (porfimer sodium in this trial) and an intense light source to kill tumor cells. Photodynamic therapy may decrease the patients' symptoms and improve their quality of life.

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Roswell Park Comprehensive Cancer Center

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Sai Yendamuri, MD, FACS

Sai Yendamuri, MD, FACS

Chair, Department of Thoracic Surgery
Professor of Oncology
Attending Surgeon, Department of Thoracic Surgery
Director, Thoracic Surgery Laboratory

Education and Training: MD - All India Institute of Medical Sciences, New Delhi, India Residency: MD Anderson Cancer Center, Houston, TX New York Hospital Medical Center of Queens/Cornell University, New York, NY Christiana ...

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