Hyperparathyroidism Reveals Two Malignancies in 27-Year-Old Patient

Gary Mann, MD, FACS, Professor of Oncology in the Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center, recounts an unexpectedly complicated series of surgeries performed on a 27-year-old patient, initially examined for hypercalcemia. The patient ultimately benefitted from the access to a multidisciplinary team of specialists available at Roswell Park, instead of needing to travel to multiple locations for diagnosis and treatment.

The initial surgery found only moderate enlargement of the patient’s parathyroid and, despite the expectation that his thyroid hormone levels would decrease after surgery from their very high levels in the 500 pg/mL range down to a more normal range of around 65 pg/mL, his levels actually increased a little. A lower left gland was removed and the patient was diagnosed with thyroid cancer, found in a node separate from the thyroid gland. However, no additional abnormal glands were found, leading Dr. Mann to order a CT scan of the patient’s chest. During that scan, the patient was found to have bilateral tumors on his kidneys, measuring 4.5 centimeters on the left adrenal gland and 3.5 centimeters on the right adrenal gland. Eventually the patient was diagnosed with hyperparathyroidism, medullary thyroid cancer, bilateral pheochromocytoma and multiple endocrine neoplasia symptom.

Thanks to the multidisciplinary, comprehensive approach embodied at Roswell Park Comprehensive Cancer Center, the patient is now doing well and is receiving medication to help keep his hormone levels stable. In other centers or medical facilities, a complicated case such as this one might have required referrals to specialists or practitioners at several different offices; at Roswell Park, the patient worked with the same team of doctors and specialists throughout his treatment and had access to experts working in tandem to diagnose and treat his condition.

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Roswell Park Comprehensive Cancer Center

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Gary Mann MD, FACS

Gary Mann MD, FACS

Surgical Oncology

Specializing In: Gastrointestinal surgical oncology, Colorectal and pancreatic surgery, HIPEC, Endocrine surgery, Appendiceal, Adrenal and Abdominal/truncal soft tissue neoplasms,Thyroid neoplasms and Hyperparathyroidism, Peritoneal surface malignancies

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